PAN Bing  Associate Professor

Contact Information

E-mail: panbing@bjmu.edu.cn

Specialism

Metabolism and vascular homeostasis; Lipoproteins and Vascular Function

Personal Profile

Graduated from Tsinghua University and Peking Union Medical College in 2008 with a Doctor of Medicine degree; Joined the Cardiovascular Metabolism and Proteomics Research Group at Peking University Institute of Cardiovascular Sciences, mainly engaged in the study of lipoproteins and vascular function; Published over 50 SCI papers in Cardiovasc Res, Redox biology, BBA, Free Radic Biol Med, Gastroenterology, and so on. So far, I have undertaken and participated in more than 10 research projects funded by the National Natural Science Foundation of China, the Doctoral Program Fund of the Ministry of Education, the Beijing Natural Science Foundation, and the Yi-X Fund

Representative Paper

1. Zhou C, Lin Z, Cao H, Chen Y, Li J, Zhuang X, Ma D, Ji L, Li W, Xu S, Pan B*, Zheng L*. Anxa1 in smooth muscle cells protects against acute aortic dissection. Cardiovasc Res. 2021. cvab109. doi: 10.1093/cvr/cvab109.

2. Li J, Chen Y, Gao J, Chen Y, Zhou C, Lin X, Liu C, Zhao M, Xu Y, Ji L, Jiang Z, Pan B*, Zheng L*. Eva1a ameliorates atherosclerosis by promoting re-endothelialization of injured arteries via Rac1/Cdc42/Arpc1b. Cardiovasc Res. 2021.117(2): 450-461.

3. He D, Zhao M, Wu C, Zhang W, Niu C, Yu B, Jin J, Ji L, Willard B, Mathew AV, Chen YE, Pennathur S, Yin H, He Y, Pan B*, Zheng L*. Apolipoprotein A-1 mimetic peptide 4F promotes endothelial repairing and compromises reendothelialization impaired by oxidized HDL through SR-B1. Redox Biol. 2018. 15: 228-242.

4. Dong M, Zhou C, Ji L, Pan B*, Zheng L*. AG1296 enhances plaque stability via inhibiting inflammatory responses and decreasing MMP-2 and MMP-9 expression in ApoE-/- mice. Biochem Biophys Res Commun. 2017. 489(4):426-431.

5. Tang Y, Pan B, Zhou X, Xiong K, Gao Q, Huang L, Xia Y, Shen M, Yang S, Liu H, Tan T, Ma J, Xu X, Mu Y, Li K. Wip1-dependent modulation of macrophage migration and phagocytosis. Redox Biol. 2017. 13:665-673.

6. Ma G, Pan B, Ren S, Guo C, Guo Y, Wei L, Zheng L, Chen B. 15-oxoeicosatetraenoic acid mediates monocyte adhesion to endothelial cell. Lipids Health Dis. 2017. 16(1):137.

7. Pan B, Kong J, Jin J, Kong J, He Y, Dong S, Ji L, Liu D, He D, Kong L, Jin DK, Willard B, Pennathur S, Zheng L. A novel anti-inflammatory mechanism of high density lipoprotein through up-regulating annexin A1 in vascular endothelial cells. Biochim Biophys Acta. 2016.1861(6):501-512.

8. Huang X, He D, Ming J, He Y, Zhou C, Ren H, He X, Wang C, Jin J, Ji L, Willard B, Pan B*, Zheng L*. High-density lipoprotein of patients with breast cancer complicated with type 2 diabetes mellitus promotes cancer cells adhesion to vascular endothelium via ICAM-1 and VCAM-1 upregulation. Breast Cancer Res Treat. 2016. 155(3):441-55.

9. Pan B, Yu B, Ren H, Willard B, Pan L, Zu L, Shen X, Ma Y, Li X, Niu C, Kong J, Kang S, Eugene Chen Y, Pennathur S, Zheng L. High-density lipoprotein nitration and chlorination catalyzed by myeloperoxidase impair its effect of promoting endothelial repair. Free radical biology & medicine. 2013. 60: 272-281.

10. Pan B, Ren H, He Y, Lv X, Ma Y, Li J, Huang L, Yu B, Kong J, Niu C, Zhang Y, Sun WB, Zheng L. HDL of patients with type 2 diabetes mellitus elevates the capability of promoting breast cancer metastasis. Clinical cancer research. 2012. 18(5): 1246-1256.