Peking University Institute of Cardiovascular Sciences
Lemin Zheng

Lemin Zheng, Ph. D.
(Email: zhengl@bjmu.edu.cn)
Vice Chair and professor of the Institute of Cardiovascular Sciences, Peking University; Member of the Party Committee, School of Basic Medical Sciences, Peking University; Distinguished "Boya" Professor of Peking University; Assistant director of National Key Laboratory; Deputy Director of Cardio-Cerebrovascular and Metabolic Department, School of Basic Medical Sciences.
National "Ten thousand Talents Plan" scientific and technological innovation leading talents (2023); National "Ten Thousand Talents Plan" Youth Top Talents; National "Excellent Youth Fund"; Ministry of Education "New Century talents".
As the first contributor, he won the first prize of the 2022 Beijing Medical Science and Technology Award and the second prize of the 2022 Beijing Science and Technology Award. He have led8 major projects funded by the National Natural Science Foundation of China (NSFC), including a major program focused on vascular research. Additionally, he participated in 6 major projects of the Ministry of Science and Technology as the project leader, and presided over 3 key projects supported by the Beijing Municipal Key Fund as well as a Beijing-Tianjin-Hebei Joint Fund project.. He was included in the "Annual Impact" list of the top 2% of global scientists in 2025.
Director of Cardiometabolic and Proteomic Research (PI), Professor, doctoral supervisor, specializing in cardiovascular pathophysiology. After graduating from the Department of Chemistry, Beijing Normal University, he joined the Chinese Academy of Sciences. In 2000, he entered the Ph.D. program between Cleveland Clinic and Cleveland State University in clinical bioanalytical chemistry. Cleveland Clinic is one of the best hospitals in the United States. After graduating with his Ph.D., he worked in a biomedical company affiliated with Cleveland Clinic. In 2007, he entered the Institute of Cardiovascular Sciences (Peking University) as a PI and associate professor; in 2015, he was promoted to professor; in 2018, he served as Vice Chair and professor of the Institute of Cardiovascular Sciences; in 2024, he was appointed as the Distinguished "Boya" Professor of Peking University.
He is currently a member of the Basic Science Group of the Cardiovascular Branch of the Chinese Medical Association, the deputy secretary-general of the Precision Medicine Branch of the Chinese Society of Cardiothoracic Anesthesiology, the leader of the Glycolipid Metabolism Group of the Vascular Branch of the Beijing Physiological Association, the member of the Cardiovascular Pharmacology Committee of the Chinese Pharmacological Society, and the member of Youth Committee of the Chinese Pathophysiology Association.
A total of 140 SCI articles have been published, and 102 are the corresponding-author paper, which are cited over 6970 times by SCI (h-index 44, Web of Science); Researchgate (https://www.researchgate.net/profile/Lemin-Zheng).
Major author articles (IF greater than 10: 31 articles; IF greater than 20: 10 articles) include:
1) Cardiovascular and cerebrovascular diseases:
European Heart Journal (IF=35.6, 2021); Neuron(IF=15.0, 2023);Nature Communications(IF=15.7, 2025,2022); Advanced Science(IF=14.1, 2025, 2023, 2022, 2021); Cardiovascular Research(IF=13.3, 2021a, 2021b); Signal transduction and targeted therapy(IF=52.7, 2023); Science Bulletin(IF=21.1, 2025, 2023); iMeta (IF=23.8, 2025a, 2025b, 2024, 2023) ; Stroke(2022, 2021); Circulation: Heart Failure(2021); European Heart Journal Open(2022); Arteriosclerosis, Thrombosis, and Vascular Biology(2019); Aging Cell(2018);Redox Biology(IF=11.9, 2021, 2018, 2017); Cell Death & Disease(2018).
2) Metabolic related diseases:
Signal transduction and targeted therapy(IF=52.7, 2024);Cell Metabolism(IF=30.9 , 2023); Gastroenterology(IF=25.1, 2020); Kidney International(IF=12.6, 2021); Research (IF=10.7, 2025); Diabetes(2021); Molecular Cancer(IF= 33.9, 2014); Clinical Cancer Research(IF=13.3, 2012).
3) Clinical translational research of cardiovascular and cerebrovascular diseases:
Advanced Materials (IF=26.8, 2020); Advanced Functional Materials (IF=19.0, 2024, 2020, 2017);Nano Letters(IF=9.1, 2021); Biosensors and Bioelectronics(IF=11.9, 2022);Nano Research(IF=9.0, 2020).
In 2010, the invention patent passed the U.S. Patent Office and the European Patent Office, and a total of 8 Chinese patents were obtained in 2019-2025 (the first inventor). In 2014, he obtained a national CFDA cardiovascular clinical medical test kit, and in 2020, he obtained 9 clinical medical test kit from CFDA. His edited monograph HDL Metabolism and Diseases, was published by Springer Nature in May 2022.
He serves as a subeditor of Cardiovascular Drugs and Therapy, Frontiers in Cardiovascular Medicine, View Medicine, The Journal of Cardiovascular Aging. He also serves on the editorial board of the SCI journals, such as Genes & Diseases and Biology. He is also a founding editor of the international magazine Global Translational Medicine (https://www.accscience.com/journal/GTM).
Research Interests
1. Study on the effects of metabolic pathways on cardiovascular and cerebrovascular homeostasis and disease mechanisms. Cardiac and vascular functional homeostasis is closely related to their metabolic states, and metabolic pathways are widely involved in the occurrence and development of cardiovascular and cerebrovascular diseases (such as aneurysms, myocardial infarction, stroke, etc.). Metabolic regulation is an important research field after gene regulation and protein regulation. The team identified a variety of metabolic molecules and pathways involved in new pathophysiological mechanisms of cardiovascular disease and key target proteins, including macrophages activating inflammatory responses through the release of succinic acid; Cell connexin Cx43 maintains vascular endothelial barrier function by regulating NAD+ levels. In aneurysmal state, GSDMD in smooth muscle cells mediated the release of putressin and phenotypic transition. Leptin aggravates aortic dissection by affecting energy metabolism and phenotypic transformation of smooth muscle cells. New mechanisms of lipid metabolism such as apo(a) and lipoprotein signaling pathways affecting the cardiovascular system.
2. Discovery of new active factors derived from endogenous and intestinal flora and their metabolic regulation. In cardiovascular and cerebrovascular disease-related population samples, we identified multiple active factors through multi-omics methods, and found their effects and mechanisms on metabolic related diseases such as diabetes, fatty liver, and tumors. Among them, we demonstrated that the endogenous factor membranin A1 acts on different cell types and plays a protective role in arterial dissection, diabetic nephropathy and obesity, and vascular endothelial metabolism regulates angiogenesis and tumor progression in tumors. Intestinal flora is another important source of human metabolism. The changes of metabolic spectrum caused by intestinal flora disturbance in the course of disease further affect the course of disease, thus generating new theoretical systems such as enteric axis, enteric brain axis and enteric liver axis. For the first time, the team identified a new metabolic product of intestinal flora, trimethylaminovaleric acid (TMAVA), and clarified its mechanism of aggravating fatty liver and heart hypertrophy. It also developed a mass spectrometry method for the detection of trimethylamine oxide (TMAO), an important metabolic product of intestinal flora activity, and discovered its new physiological functions in stroke and pulmonary hypertension. We also revealed that aging-associated gut microbiota and their metabolites affect the host drug efflux mechanism. Through metabolic intervention and metabolism related regulation, we put forward new ideas and insights on the treatment of cardiovascular and cerebrovascular diseases and metabolic related diseases.
3. Combined with new materials and technologies to carry out translational medicine research on cardio-cerebrovascular related diagnosis and treatment. The application of new technologies to develop cardiovascular and cerebrovascular disease diagnosis and treatment methods, including the use of biological and nanomaterials equipped with imaging groups or pharmacological components to achieve non-invasive imaging or targeted therapy for diseases such as arterial plaque, the use of molecular probes and structural prediction to develop related drugs to correct disease metabolic disorders, the optimization of clinical mass spectrometry detection methods to develop a multi-indicator comprehensive warning system for cardiovascular and cerebrovascular diseases, etc. The diagnosis and treatment of cardiovascular and cerebrovascular diseases can continue to develop on the new track.
40 representative SCI papers (* as the corresponding author) :
1. Cheng Cui #, Lu Fang #, Lei Li#, Xuan Lai , Ruitao Zhang , Qi Zhang, Rong Miao, Gaofei Hu, Miao Zhang , Jie En Valerie Sia , Jingcheng Chen , Haodi Chai , Xinyi Wu, Zijin Lin, Fan Zhang , Haiyan Li , *Lemin Zheng , *Dongyang Liu.Odoribacter splanchnicus rescues aging-related intestinal P-glycoprotein damage via GDP-L-fucose secretion. Nat Commun. 2025 Nov 27;16(1):10665. (IF=15.7, JCR=Q1)
2. Nana Yang#, Jiahong Chen#, Yujie Zhu#, Wenxin Shan, Zheng Cao, Yiwen Fu, Huanhuan Cao, Yanyan Li, Yukun Xiang, Shusi Ding, Huiqing Wang, Yaobo Zhao,Liang Ji, Rui Zhan,Yufei Wu,Zhaomeng Wang,*Manyuan Dong, *Lemin Zheng. Human cardiac organoid model reveals antibacterial triclocarban promotes myocardial hypertrophy by interfering with endothelial cell metabolism. Science bulletin. 2025 Feb 15;70(3):342-346. (IF=21.1, JCR=Q1)
3. Shilun Wu#, Changyu Yao#, Lu Fang#, Yiwen Sun, Mingming Zhao, Jie Chen, Gaofei Hu, Zhe Zhao, Shusi Ding, Jing Xue, Xiaoyi Liu, *Wenbing Su, *Jian Kong, *Lemin Zheng. ATPase Inhibitory Factor 1 Drives Mitochondrial Energy Metabolic Reprogramming to Promote HCC Vasculogenic Mimicry via the ESR1/miR-20a-3p/GNAZ Pathway. Research (Wash D C). 2025 Nov 25;8:0998. (IF=10.9, JCR=Q1)
4. Ling Chen#, Yujie Zhu#, Xi Yang, JiangBin Wu, Keyuan Chen, Wuqing Huang, Lu Fang, Qi Zhang, Jie Chen, Jianing Gao, Huanhuan Cao, Meifang Wu, Zhihuang Qiu, Yuling Zhang, Yue Shen, Qiuyu Huang, Zhiyong Lin, *Lemin Zheng, *Liangwan Chen. Leptin Aggravates Thoracic Aortic Dissection Through Impairment of Energy Metabolism in Nrip2+ Smooth Muscle Cells. Advanced Science (Weinh). 2025 Jul 16:e02027. (IF=14.1, JCR=Q1)
5. Luyun Fan#,Junru Chen#,Qi Zhang#,Jie Ren#,Youren Chen#, Jinfeng Yang#, Lu Wang#, Zihong Guo, Peili Bu, Bingpo Zhu, Yanyan Zhao, Yang Wang, Xiaoyan Liu, Wenjie Wang, Zhenzhen Chen, Qiannan Gao,*Lemin Zheng,*Jun Cai. Fecal microbiota transplantation for hypertension: an exploratory, multicenter, randomized, blinded, placebo-controlled trial. Microbiome.2025 May 23;13(1):133. (IF=13.8, JCR=Q1)
6. Chengjun Zheng#, Peng Wang#, Delong Zhang#, Zheng Fang, Yutong Feng, Jie Chen, Jiahong Chen, Yiwen Fu, Bao Yang, Shuqing Yu, Li Min, Bo Xiao, Cencan Xing, Yang Yang, Jianfeng Wang, Donghua Zou, Shipeng Ning, Tong Liu, Jun Yan, Qian Zhao, Fei Sun, Qiaodong Chen, Ying Zhang, *Tao Jiang, *Lemin Zheng, *Zhaoshi Bao. A novel organoid model retaining the glioma microenvironment for personalized drug screening and therapeutic evaluation. Bioactive Materials. 2025 Jul 14;53:205-217.(IF=20.3, JCR=Q1)
7. Zhe Zhao, Jing Chen, Yixuan Liu, Shiqi Wang, Danhua Zhao, Chaobo Bai, Meifang Wu, Gaofei Hu, Yiwen Fu, Lu Fang, Xiaoyi Liu, Zheng Zhang, Rui Zhan, *Lemin Zheng, *Junliang Yuan. Multi-omics identifies microbiota-derived deoxycholic acid as a key mediator of blood-brain barrier dysfunction in Parkinson’s disease. iMeta. 2025 Sep 17;4(5):e70076. . (IF=33.2, JCR=Q1)
8. Xu Lin#, Zuxiang Yu#, Yang Liu#, Changzhou Li#, Hui Hu#, Jia-Chun Hu#, Mian Liu#, Qin Yang, Peng Gu, Jiaxin Li, Kutty Selva Nandakumar, Gaofei Hu, Qi Zhang, Xinyu Chen, Huihui Ma, Wenye Huang, *Gaofeng Wang, *Yan Wang, *Liping Huang, *Wenjuan Wu, *Ning-Ning Liu, *Chenhong Zhang, *Xingyin Liu, *Lemin Zheng, *Peng Chen. Gut-X axis. iMeta. 2025 Feb 26;4(1):e270. (IF=23.8, JCR=Q1)
9. Lu Fang#, Changjie Liu#, Zong-Zhe Jiang, Mengxiao Wang, Kang Geng, Yangkai Xu, Yujie Zhu, Yiwen Fu, Jing Xue, Wenxin Shan, Qi Zhang, Jie Chen, Jiahong Chen, Mingming Zhao, Yuxuan Guo, K W Michael Siu, Y Eugene Chen, *Yong Xu, *Donghui Liu, *Lemin Zheng. Annexin A1 binds PDZ and LIM domain 7 to inhibit adipogenesis and prevent obesity. Signal transduction and targeted therapy. 2024 Aug 23;9(1):218. (IF=52.7, JCR:Q1)
10. Jiageng Cai#, Xiaoxiao Ge#, Shiyu Lu, Yabin Wang, Hongtu Cui, Rui Zhan, Sheng'e Su, Wenxin Shan, Zhulan Cai, Cencen Wu, Yuan Xu, Penghui Zhao, Yanyan Li, Yue Lan, Le Sun, *Shaojun Guo, *Lemin Zheng, *Lingyun Zu. Au/FeNiPO4-Based Multiple Spectra Optoacoustic Tomography/CT Dual-Mode Nanoprobe for Systemic Screening of Atherosclerotic Vulnerable Plaque. Advanced Functional Materials. 2024 May 29. (IF=19.0, JCR=Q1)
11. Rui Zhan#, Xia Meng#, Dongping Tian, Jie Xu, Hongtu Cui, Jialei Yang, Yangkai Xu, Mingming Shi, Jing Xue, Weiwei Yu, Gaofei Hu, Ke Li, Xiaoxiao Ge, Qi Zhang, Mingming Zhao, Jianyong Du, Xin Guo, Wenli Xu, Yang Gao, Changyu Yao, Fan Chen, Yue Chen, Wenxin Shan, Yujie Zhu, Liang Ji, Bing Pan, Yan Yu, Wenguang Li, Xuyang Zhao, Qihua He, Xiaohui Liu, Yue Huang, Shengyou Liao, Bin Zhou, Dehua Chui, Y Eugene Chen, Zheng Sun, *Erdan Dong, *Yongjun Wang, *Lemin Zheng. NAD+ rescues aging-induced blood-brain barrier damage via the CX43-PARP1 axis. Neuron. 2023 Aug 29:S0896-6273(23)00622-0. (IF=15.0, JCR=Q1)
12. Pengxiang Qu#, Oren Rom#, Ke Li#, Linying Jia, Xiaojing Gao, Zhipeng Liu, Shusi Ding, Mingming Zhao, Huiqing Wang, Shuangshuang Chen, Xuelian Xiong, Ying Zhao, Chao Xue, Yang Zhao, Chengshuang Chu, Bo Wen, Alexandra C. Finney, Zuowen Zheng, Wenbin Cao, Jinpeng Zhao, Liang Bai, Sihai Zhao, Duxin Sun, Rong Zeng, Jiandie Lin, Wanqing Liu, *Lemin Zheng, *Jifeng Zhang, *Enqi Liu, Y. *Eugene Chen. DT-109 ameliorates nonalcoholic steatohepatitis in nonhuman primates. Cell Metabolism. 2023 May 2;35(5):742-757.e10. (IF=30.9, JCR=Q1)
13. Zekun Wang#, Nana Yang#, Yajun Hou, Yuqing Li, Chenyang Yin, Endong Yang, Huanhuan Cao, Gaofei Hu, Jing Xue, Jialei Yang, Ziyu Liao, Weiyun Wang, *Dongdong Sun, *Cundong Fan, *Lemin Zheng. L-Arginine-Loaded Gold Nanocages Ameliorate Myocardial Ischemia/Reperfusion Injury by Promoting Nitric Oxide Production and Maintaining Mitochondrial Function. Advanced science (Weinh). 2023 Sep;10(26):e2302123. (IF=14.3, JCR=Q1)
14. Jianing Gao#, Huanhuan Cao, Gaofei Hu, Yufei Wu, Yangkai Xu, Hongtu Cui, Hong S Lu, *Lemin Zheng. The mechanism and therapy of aortic aneurysms. Signal transduction and targeted therapy. 2023 Feb 3;8(1):55. (IF=52.7, JCR=Q1)
15. Qingyuan Liu#, Ke Li#, Hongwei He, Zengli Miao, Hongtu Cui, Jun Wu, Shusi Ding, Zheng Wen, Jiyuan Chen, *Xiaojie Lu, *Jiangan Li, *Lemin Zheng, *Shuo Wang. The markers and risk stratification model of intracranial aneurysm instability in a large Chinese cohort. Science bulletin. 2023 May 10:S2095-9273(23)00308-0. (IF=21.1, JCR=Q1)
16. Huanhuan Cao, Yujie Zhu, Gaofei Hu, Qi Zhang, *Lemin Zheng. Gut microbiome and metabolites, the future direction of diagnosis and treatment of atherosclerosis? Pharmacological Research. 2023 Jan;187:106586. (IF=10.5, JCR=Q1)
17. Mingming Zhao#, Haoran Wei#, Chenze Li, Rui Zhan, Changjie Liu, Jianing Gao, Yaodong Yi, Xiao Cui, Wenxin Shan, Liang Ji, Bing Pan, Si Cheng, Moshi Song, Haipeng Sun, Huidi Jiang, Jun Cai, Minerva Garcia-Barrio, Y. Eugene Chen, Xiangbao Meng, Erdan Dong, *Dao Wen Wang, *Lemin Zheng. Gut microbiota production of trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy. Nature Communications. 2022 Apr 1;13(1):1757. (IF=15.7, JCR=Q1)
18. Jianing Gao#, Yanghui Chen#, Huiqing Wang, Xin Li, Ke Li, Yangkai Xu, Xianwei Xie, Yansong Guo, Nana Yang, Xinhua Zhang, Dong Ma, Hong S Lu, Ying H Shen, Yong Liu, Jifeng Zhang, Y Eugene Chen, Alan Daugherty, *Dao Wen Wang, *Lemin Zheng. Gasdermin D Deficiency in Vascular Smooth Muscle Cells Ameliorates Abdominal Aortic Aneurysm Through Reducing Putrescine Synthesis. Advanced Science (Weinh). 2022 Dec 25:e2204038. (IF=14.3, JCR=Q1)
19. Yang Y#, Zeng Q#, Gao J#, Yang B, Zhou J, Li K, Li L, Wang A, Li X, Liu Z, Luo Q, Zhao Z, Liu B, Xue J, Jiang X, Konerman MC, * Zheng L, *Xiong C. High-circulating gut microbiota-dependent metabolite trimethylamine N-oxide is associated with poor prognosis in pulmonary arterial hypertension. European Heart Journal Open. 2022 Mar 29;2(5):oeac021.
20. Xu J#, Hao X#, Zhan R#, Jiang X, Jin A, Xue J, Cheng A, Liu J, Lin J, Meng X, Li H, *Zheng L, *Wang Y. Effect of Lipoprotein(a) on Stroke Recurrence Attenuates at Low LDL-C (Low-Density Lipoprotein) and Inflammation Levels. Stroke. 2022 Aug;53(8):2504-2511. (JCR=Q1)
21. Xiao-Xiao Chen#, Yufei Wu#, Xiaoxiao Ge, Liandi Lei, *Li-Ya Niu, *Qing-Zheng Yang, *Lemin Zheng. In vivo imaging of heart failure with preserved ejection fraction by simultaneous monitoring of cardiac nitric oxide and glutathione using a three-channel fluorescent probe. Biosensors and Bioelectronics. 2022 Oct 15;214:114510.(IF=11.9, JCR=Q1)
22. Xu J#, Cheng A#, Song B, Zhao M, Xue J, Wang A, Dai L, Jing J, Meng X, Li H, *Zheng L, *Wang Y. Trimethylamine N-Oxide and Stroke Recurrence Depends on Ischemic Stroke Subtypes. Stroke. 2022 Apr;53(4):1207-1215. (JCR=Q1)
23. Cui H#, Chen Y#, Li K, Zhan R, Zhao M, Xu Y, Lin Z, Fu Y, He Q, Tang PC, Lei I, Zhang J, Li C, Sun Y, Zhang X, Horng T, Lu HS, Chen YE, Daugherty A, *Wang D, *Lemin Zheng. Untargeted metabolomics identifies succinate as a biomarker and therapeutic target in aortic aneurysm and dissection. European Heart Journal. 2021 Nov 7;42(42):4373-4385. (IF=37.6, JCR=Q1)
24. Wu L#, Liu C#, Chang DY, Zhan R, Sun J, Cui SH, Eddy S, Nair V, Tanner E, Brosius FC, Looker HC, Nelson RG, Kretzler M, Wang JC, Xu M, Ju W, Zhao MH, *Chen M, *Lemin Zheng. Annexin A1 alleviates kidney injury by promoting the resolution of inflammation in diabetic nephropathy. Kidney International. 2021 Jul;100(1):107-121. (IF=12.6, JCR=Q1)
25. Jiang X, Xu J, Hao X, Xue J, Li K, Jin A, Lin J, Meng X, *Zheng L, *Wang Y. Elevated lipoprotein(a) and lipoprotein-associated phospholipase A2 are associated with unfavorable functional outcomes in patients with ischemic stroke. Journal of Neuroinflammation. 2021 Dec 28;18(1):307. (IF=10.1, JCR=Q1)
26. Xu J#, Zhao M#, Wang A, Xue J, Cheng S, Cheng A, Gao J, Zhang Q, Zhan R, Meng X, Xu M, Li H, Zheng L*, Wang Y*. Association Between Plasma Trimethyllysine and Prognosis of Patients With Ischemic Stroke. Journal of the American Heart Association. 2021 Dec 7;10(23):e020979. (JCR=Q1)
27. Li C#, Zhao M#, Xiao L, Wei H, Wen Z, Hu D, Yu B, Sun Y, Gao J, Shen X, Zhang Q, Cao H, Huang J, Huang W, Li K, Huang M, Ni L, Yu T, Ji L, Xu Y, Liu G, Konerman MC, *Lemin Zheng, *Wang D. Prognostic Value of Elevated Levels of Plasma N-Acetylneuraminic Acid in Patients With Heart Failure. Circulation: Heart Failure. 2021 Nov;14(11):e008459 (JCR=Q1)
28. Wu L#, Liu C#, Chang D Y, Zhan R, Zhao M, Lam S M, Shui G, Zhao M H, *Lemin Zheng, *Chen M. The attenuation of diabetic nephropathy by annexin A1 via regulation of lipid metabolism through AMPK/PPARα/CPT1b pathway. Diabetes. 2021 Oct;70(10):2192-2203. (JCR=Q1)
29. Zhou C, Lin Z, Cao H, Chen Y, Li J, Zhuang X, Ma D, Ji L, Li W, Xu S, *Pan B, *Lemin Zheng. Anxa1 in smooth muscle cells protects against acute aortic dissection. Cardiovascular Research. 2021 Mar 23:cvab109. (IF=13.3, JCR=Q1)
30. Jingxuan Li#, Yingyu Chen#, Jianing Gao, Yue Chen, Changping Zhou, Xin Lin, Changjie Liu, Mingming Zhao, Yangkai Xu, Liang Ji, Zongzhe Jiang, *Bing Pan, *Lemin Zheng. Eva1a ameliorates atherosclerosis by promoting re-endothelialization of injured arteries via Rac1/Cdc42/Arpc1b. Cardiovascular Research. 2021 Jan 21;117(2):450-461. (IF=13.3, JCR=Q1)
31. Jian Kong#, Changyu Yao#, Shuying Dong#, Shilun Wu, Yangkai Xu, Ke Li, Liang Ji, Qiang Shen, Qi Zhang, Rui Zhan, Hongtu Cui, Changping Zhou, Haigang Niu, Guoming Li, *Wenbing Sun, *Lemin Zheng. ICAM-1 Activates Platelets and Promotes Endothelial Permeability through VE-cadherin after Insufficient Radiofrequency Ablation. Advanced Science (Weinh). 2021 Jan 4;8(4):2002228. (IF=14.3, JCR=Q1)
32. Man Z, Cui H, Lv Z, Xu Z*, Wu Z, Wu Y, Liao Q, Liu M, Xi P*, Zheng L*, Fu H*. Organic Nanoparticles-Assisted Low-Power STED Nanoscopy. Nano Letters. 2021 Apr 28;21(8):3487-3494. (JCR=Q1)
33. Zhang M#, Gao J#, Zhao X, Zhao M, Ma D, Zhang X, Tian D, Pan B, Yan X, Wu J, Meng X, Yin H, *Lemin Zheng. p38α in macrophages aggravates arterial endothelium injury by releasing IL-6 through phosphorylating megakaryocytic leukemia 1. Redox Biology. 2021 Jan;38:101775. (IF=11.9, JCR=Q1)
34. Mingming Zhao#, Lin Zhao#, Xuelian Xiong, Yuan He, Wei Huang, Zihao Liu, Liang Ji, Bing Pan, Xuefeng Guo, Leibo Wang, Si Cheng, Ming Xu, Hongyuan Yang, Yuxin Yin, Minerva T. Garcia-Barrio, Y. Eugene Chen, Xiangbao Meng, *Lemin Zheng. TMAVA, a Metabolite of Intestinal Microbes, Is Increased in Plasma From Patients With Liver Steatosis, Inhibits γ-butyrobetaine Hydroxylase, and Exacerbates Fatty Liver in Mice. Gastroenterology. 2020 Jun;158(8):2266-2281. (IF=25.1, JCR=Q1)
35. Xiaoxiao Ge#, Hongtu Cui#, Jian Kong, Shi-Yu Lu, Rui Zhan, Jianing Gao, Yangkai Xu, Shuangyan Lin, Kaixin Meng, Lingyun Zu, Shaojun Guo, *Lemin Zheng. A Non-Invasive Nanoprobe for In Vivo Photoacoustic Imaging of Vulnerable Atherosclerotic Plaque. Advanced Materials. 2020 Sep;32(38):e2000037. (IF=26.8, JCR=Q1)
36. Zheng Lv#, Zhongwei Man#, Hongtu Cui, Zhenzhen Xu*, Huanhuan Cao, Shuai Li, Qing Liao, Qihua He, Lemin Zheng*, and Hongbing Fu*. Red AIE Luminogens with Tunable Organelle Specific Anchoring for Live Cell Dynamic Super Resolution Imaging. Advanced Functional Materials. 2020, 31(10), 2009329. (IF=19.0, JCR=Q1)
37. Zheng Lv #, Li Li#, Zhongwei Man, Zhenzhen Xu*, Hongtu Cui, Rui Zhan, Qihua He, *Lemin Zheng, Hongbing Fu*. Polarity-activated super-resolution imaging probe for the formation and morphology of amyloid fibrils. Nano Research. 2020, 13(9): 2556-2563. (JCR=Q1)
38. Jianping Li#, Changping Zhou#, Hongbing Xu#, Robert Brook, Shengcong Liu, Tieci Yi, Yang Wang, Baihuan Feng, Mingming Zhao, Xu Wang, Qian Zhao, Jie Chen, Xiaoming Song, Tong Wang, Shuo Liu, Yi Zhang, Rongshan Wu, Jianing Gao, Bing Pan, Subramaniam Pennathur, Sanjay Rajagopalan, Yong Huo, *Lemin Zheng, *Wei Huang. Ambient Air Pollution is Associated with High-Density Lipoprotein Dysfunction in Healthy Adults. Arteriosclerosis, Thrombosis, and Vascular Biology. 2019 Mar;39(3):513-522. (JCR=Q1)
39. He D#, Zhao M#, Wu C, Zhang W, Niu C, Yu B, Jin J, Ji L, Willard B, Mathew A, Chen Y, Pennathur S, Yin H, He Y, *Pan B, *Lemin Zheng. Apolipoprotein A-1 mimetic peptide 4F promotes endothelial repairing and compromises reendothelialization impaired by oxidized HDL through SR-B1. Redox Biology. 2018 May;15:228-242. (IF=11.9, JCR=Q1)
40. Zhan R, Zhao M, Zhou T, Chen Y, Yu W, Zhao L, Zhang T, Wang H, Yang H, Jin Y, He Q, Yang X, Guo X, Willard B, Pan B, Huang Y, Chen Y, *Chui D, *Lemin Zheng. Dapsone protects brain microvascular integrity from high-fat diet induced LDL oxidation. Cell Death & Disease. 2018 Jun 7;9(6):683. (JCR=Q1)
Awards for doctoral students trained as supervisors (including co-supervisors) :
l Fang Lu (PhD, 2025, Zheng Lemin as supervisor): Excellent graduate of Beijing; Excellent graduate of Peking University.
l Gao Jianing (PhD, 2023, Zheng Lemin as supervisor): Excellent graduate of Peking University.
l Wu Liang (PhD, 2022, Zheng Lemin as co-supervisor): Excellent graduate of Beijing; Peking University Outstanding Graduate
l Cui Hongtu (PhD, 2021, Zheng Lemin as supervisor): Excellent graduate of Beijing; Excellent graduate of Peking University; He is the Post-doctor of the national "Bo Xin Program". He is now an associate researcher at Peking University Third Hospital.
l Yao Changyu (PhD, 2021, Zheng Lemin as co-supervisor): Excellent graduate of Beijing; Capital Medical University "Youbo".
l Zhao Mingming (PhD, 2020, Zheng Lemin as supervisor): Excellent graduate of Beijing; Excellent graduate of Peking University; He is the post-doctor of the national "Bo Xin Program". He is now an associate researcher at Peking University Third Hospital.

