Jing Liang, M.D., Ph.D.

Principal Investigator, Associate Professor with Tenure

Contact Information

Department of Biochemistry and Biophysics

Peking University, School of Basic Medical Sciences

Room 323, the Biochemistry Building 38 Xueyuan RoadHaidian District, Beijing 100191

Email: liang_jing@bjmu.edu.cn

Personal Profile

Dr. Jing Liang is Principal Investigator and Tenured Associate Professor in theDepartment of Biochemistry and Biophysics, Peking University Health Science Center. Shereceivedher MD degreefrom Peking University Health Science Center and her Ph.D. degree in Molecular and Cellular Biology from the University of Maryland, Baltimore. She joined the Department of Biochemistry and Molecular Biology in Peking Universityin 2004,and did a visiting study in Baylor College of Medicine from 2017 to 2018. She was appointed principal investigator and tenured associate professor in Peking University in 2019.She is a winner of New Century Excellent Talents from Ministry of Educationof China, andhas severed as Board Member of the Chinese Youth Society of Biochemistry and Molecular Biology in Medicine.Over the years, Dr. Liang has published over 30 peer-reviewed papers in highly impacted scientific journals including Science Advances，Nature Communications, Molecular Cell, Biological Psychiatry, EMBO Reports, Oncogene et al. Her research was funded by National Natural Science Foundation, Ministry of Science and Technology, and Ministry of Education.

Research of Focus

Histone modifications represent important mechanisms of the epigenetic regulatory network that dictates a wide range of biological processes including replication, transcription, and DNA damage repair. We are interested in deciphering the molecular mechanisms of the writer, eraser, and reader proteins of histone modificationsin regulating chromatin-based events and in mediating the crosstalk between metabolic and epigenetic rewiring during development and cancer. We have studied the genetic and epigenetic mechanisms of a series of transcription factors and cofactors during cancer development especially breast carcinogenesis.Representative studies also include a series of work investigating the role of Chromodomain Y-like (CDYL) protein, a histone methyllysine reader and a crotonyl-CoA hydratase, in mediating transcriptional repression, epigenetic inheritance and histone modification crosstalk during various biological processes such as cancer, spermatogenesis, neurological diseases.

Staff

Research Associate : Dr.Jianying Liu,Email:liujianying@bjmu.edu.cn

Technician: Ms. Xin Wu,Email:wuxin12@bjmu.edu.cn