Pingzhang Wang, Associate Professor (PhD Supervisor)

Contact Information

wangpzh@bjmu.edu.cn

Research Direction

Systems immunology & immunoinformatics; Functional genomics and plasticitomics

Personal profile

Dr. Pingzhang Wang focuses on the study of plasticitomics, which examines gene plasticity at multiple levels to explore the rules of dynamic changes in life molecules, the underlying mechanisms, and applications based on gene plasticity. His research interests include developing new concepts and theories driven by omics big data. Dr. Wang proposes a theoretical framework for classifying and discovering immune cell phenotypes based on gene plasticity. He also explores application scenarios such as evaluating marker genes, discovering novel immune cell functional subsets, and identifying co-phenotypes and mutually exclusive phenotypes driven by internal phenotypic regulation. Additionally, Dr. Wang has successfully predicted multiple novel human cytokines and CD antigens based on immunoinformatics analysis. He has also conducted a systematic analysis of truncated transcriptional variants with intronic polyadenylation in the human genome. To date, Dr. Wang has undertaken six projects from the National Natural Science Foundation of China and two from the Beijing Natural Science Foundation. Dr. Wang has published over 30 SCI papers as the first or corresponding author (including co-first and co-corresponding) in journals such as Cellular & Molecular Immunology, Journal of Autoimmunity, Journal of Immunology, European Journal of Immunology, Immunology, Journal of Leukocyte Biology, Nucleic Acids Research, Database, and BMC Genomics. He has also obtained multiple patent authorizations.