kai wang assistant professor

Connact Information

Kai.wang88@pku.edu.cn

Research Areas

Stem Cells and Cardiovascular Organoids

Personal Profile

Professor Kai Wang is an Assistant Professor in the Department of Physiology and Pathophysiology, Peking University. He also serves as a PI in the State Key Laboratory of Vascular Homeostasis and Remodeling. He earned his Ph.D degree at Peking University and finished his postdoctoral training in Harvard Medical School/Boston Children’s Hospital and Cornell University from 2016 to 2021. His lab focuses on the interdisciplinary research on the stem cells and vascular organoid. He now serves as Associate Editor in the journal of Microvascular Research and Cell Transplantation. He has published 18 peer-reviewed papers in highly impacted scientific journals including Cell Stem Cell, Sci Adv, Adv Sci, Adv Mat, Biomaterials and et al. He also serves as ad hoc reviewer for journals including Cell Stem Cell, Sci Adv, ACS Nano, Angiogenesis and et al.

Experience

2006-2010  southeast University，Bachelor

2010-2016  peking university, PhD

2016-2021  Harvard Medical School, Post doc

2021-present  peking university, Assistant Professor

Representative Publications

Liyan Gong, Yadong Zhang, Yonglin Zhu, Umji Lee, Allen Chilun Luo, Xiang Li, Xi Wang, Danyang Chen, William T. Pu, Ruei-Zeng Lin, Minglin Ma, Miao Cui, Kaifu Chen, Kai Wang*, Juan M. Melero-Martin*. Rapid generation of functional vascular organoids via simultaneous transcription factor activation of endothelial and mural lineages.  Cell Stem Cell , 2025 Jun 10:S1934-5909(25)00221-8.(Previews & Cover)

Yun Zhao^#, Mengze Sun^#, Zihang Pan^#, Weijing Kong, Zixuan Hong, Wei Zhang, Bingbing Sun, Jingjing Zhang*, Xi Wang*, Kai Wang*. A novel quantitative angiogenesis assay based on visualized vascular organoid.  Angiogenesis , 2025 Jan 3;28(1):10. doi: 10.1007/s10456-024-09967-z

Zihang Pan^#, Qiyang Yao^#, Weijing Kong, Xiaojing Ma, Liangliang Tian, Yun Zhao, Shuntian Zhu, Sheng Chen, Mengze Sun, Jiao Liu, Simin Jiang, Jianxun Ma, Qijia Liu, Xiaohong Peng, Xiaoxia Li, Zixuan Hong, Yi Hong, Xue Wang, Jiarui Liu, Jingjing Zhang, Wei Zhang, Bingbing Sun, Sara Pahlavan,Youchen Xia, Weimin Shen, Yuyong Liu, Wenjian Jiang, Zhengwei Xie*, Wei Kong,* Xi Wang,* Kai Wang*. Generation of iPSC-derived venous endothelial cells for the modeling of vascular malformation and drug discovery.  Cell Stem Cell , 2025,32(2),227-245. Doi: 10.1016/j.stem.2024.10.015  （Previews）

Umji Lee^#, Yadong Zhang^#, Yonglin Zhu, Allen Chilun Luo, Liyan Gong, Daniel M. Tremmel, Yunhye Kim, Victoria Sofia Villarreal, Xi Wang, Ruei-Zeng Lin, Miao Cui, Minglin Ma, Ke Yuan, Kai Wang*, Kaifu Chen*, Juan M. Melero-Martin*. Robust differentiation of human pluripotent stem cells into mural progenitor cells via transient activation of NKX3.1.  Nature Communications , 2024, 15 (1), 8392. doi:10.1038/s41467-024-52678-8

Xuanyu Liu^#, Qingyi Zeng^#, Hang Yang, Wenke Li, Qianlong Chen, Kunlun Yin, Zihang Pan, Kai Wang*, Mingyao Luo*, Chang Shu*, Zhou Zhou*. Single-nucleus Multiomic Analyses Identifies Gene Regulatory Dynamics of Phenotypic Modulation in Human Aneurysmal Aortic Root.  Advanced Science , 2024, 11(22), e2400444. doi:10.1002/advs.202400444

Kai Wang, Ruei-Zeng Lin, Alex H. Ng, Xuechong Hong, Chin Nien Lee, Joseph Neumeyer, Gang Wang, Xi Wang, Minglin Ma, William T. Pu, George M. Church, Juan M. Melero-Martin*, Robust Differentiation of Human Pluripotent Stem Cells into Endothelial Cells via Temporal Activation of ETV2 with Modified mRNA.  Science Advances  2020; 6(30): eaba7606. Doi: 10.1126/sciadv.aba7606