孙祺，研究员， 助理教授， 博士生导师

北京大学干细胞再生医学中心PI

地址：北京市海淀区学院路38号

北京大学医学科技北楼1302房间

电子邮箱：sunq01@hsc.pku.edu.cn

教育与工作经历：

2007.9 - 2011.6：中国药科大学药学专业本科

2011.9 - 2018.12：美国纽约大学药理学专业博士

2019.1 - 2024.2：美国纽约大学医学院博士后

2024.3 - 今：北京大学干细胞研究中心研究员

主要研究方向：

1. 成体干细胞的稳态维持和组织再生；

2. 白发生成的原因和干预策略；

3. 黑色素瘤发生发展的机制研究。

代表论文：

1. Sun Q, Brinks A, Ito M. Reversible Differentiation of Melanocyte Stem Cells: Designed to Last or Be Lost? J Invest Dermatol. 2023 Sep 7:S0022-202X(23)02482-X. doi: 10.1016/j.jid.2023.06.207. PMID: 37676220.

2. Sun Q, Lee W, Hu H, Ogawa T, De Leon S, Katehis I, Lim CH, Takeo M, Cammer M, Taketo MM, Gay DL, Millar SE, Ito M. Dedifferentiation maintains melanocyte stem cells in a dynamic niche. Nature. 2023 Apr;616(7958):774-782.PMCID: PMC10132989.

3. Sun Q#, Lee W#, Mohri Y, Takeo M, Lim CH, Xu X, Myung P, Atit RP, Taketo MM, Moubarak RS, Schober M, Osman I, Gay D, Nishimura EK, Ito M. A novel melanoma mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease. Nat Commun. 2019 Nov 4;10(1):5023. PMCID:PMC6828673. # Contributed equally.

4. Lim CH, Sun Q, Ratti K, Lee SH, Zheng Y, Takeo M, Lee W, Rabbani P, Plikus MV, Cain JE, Wang DH, Watkins DN, Millar S, Taketo MM, Myung P, Cotsarelis G, Ito M. Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing. Nat Commun. 2018 Nov 21;9(1):4903. PMCID: PMC6249328

5. Sun Q, Rabbani P, Takeo M, Lee SH, Lim CH, Noel ES, Taketo MM, Myung P, Millar S, Ito M. Dissecting Wnt signaling for melanocyte regulation during wound healing. J Invest Dermatol. 2018 Jul;138(7):1591-1600. PMCID: PMC6019608

6. Takeo M, Lee W, Rabbani P, Sun Q, Hu H, Lim CH, Manga P, Ito M. EdnrB Governs Regenerative Response of Melanocyte Stem Cells by Crosstalk with Wnt Signaling. Cell Report. 2016 May 10;15(6):1291-302. PMCID: PMC5391032

7. Takeo M, Chou WC, Sun Q, Lee W, Rabbani P, Loomis C, Taketo MM, Ito M. Wnt activation in nail epithelium couples nail growth to digit regeneration. Nature. 2013 Jul 11;499(7457):228-32. PMCID: PMC3936678

8. Sun Q, Chen L, Gao M, Jiang W, Shao F, Li J, Wang J, Kou J, Yu B. Ruscogenin inhibits lipopolysaccharide-induced acute lung injury in mice: involvement of tissue factor, inducible NO synthase and nuclear factor (NF)-κB. Int Immunopharmacol. 2012 Jan;12(1):88-93. PMID: 22079591

9. Gao M, Chen L, Yu H, Sun Q, Kou J, Yu B. Diosgenin down-regulates NF-κB p65/p50 and p38MAPK pathways and attenuates acute lung injury induced by lipopolysaccharide in mice. Int Immunopharmacol. 2013 Feb;15(2):240-5. PMID: 23246979

10. Sun Q, Shao F, Li J, Wang J, Kou J, Yu B. Advances in studies on active components modulating tissue factor in Chinese materia medica; Chinese Traditional and Herbal Drugs; 2010:41(3):488-91.