导师介绍
姚伟娟 副教授

姚伟娟,副教授,硕士研究生导师
联系方式
办公地点:生理楼312室
邮箱: weijuanyao@bjmu.edu.cn
联系电话: 010-82802419,13717802916
研究方向
心血管疾病的力学生物学机制
个人简介
2002年6月在北京大学医学部获得博士学位,之后赴美国加州大学圣地亚哥分校生物工程系做博士后研究,2008年9月回到北京大学医学部生理与病理生理学系工作。主要从事血管稳态和疾病中的力学生物学调控机制研究,在ATVB、Frontiers in Immunology、Cell Mol Life Sci和NPJ Regen Med等杂志上发表SCI论文四十余篇。
科研成果
Liu Y, Zhao C, Liang Z, Xu Y, Liu J, Yao WJ*, Zhou J*. APEX1-STAT3 signaling mediates the force-coordinated endothelial regeneration. Cell Mol Life Sci. 2025;82(1):321.
Wang Q#, Han JL#, Liang ZH#, Geng XY, Du YQ, Zhou J, Yao WJ*, Xu T*. FSH Is Responsible for Androgen Deprivation Therapy-Associated Atherosclerosis in Mice by Exaggerating Endothelial Inflammation and Monocyte Adhesion. Arterioscler Thromb Vasc Biol. 2024;44(3):698-719.
Geng XY, Xia X, Liang ZH, Li S, Yue ZJ, Zhang H, Guo LN, Ma S, Jiang SY, Lian X, Zhou J, Sung LA, Wang XF*, Yao WJ*. Tropomodulin1 exacerbates inflammatory response in macrophages by negatively regulating LPS-induced TLR4 endocytosis, Cell Mol Life Sci. 2024;81(1): 402.
Liu XM, Yu P, Xu YJ, Wang Y, Chen J, Tang FZ, Hu ZQ, Zhou J, Liu LN, Qiu W, Ye YN, Jia Y, Yao WJ*, Long JH*, Zeng Z*. Metformin induces tolerogenicity of dendritic cells by promoting metabolic reprogramming. Cell Mol Life Sci. 80(10):283, 2023.
Zhao CR#, Yang QR#, Tang RZ#, Wang L, Wang J, Yang FF, Zhao JN, Zhu JJ, Pang W, Li N, Zhang X, Tian XY, Yao WJ*, Zhou J*. DNA methyltransferase 1 deficiency improves macrophage motility and wound healing by ameliorating cholesterol accumulation. NPJ Regen Med. 8(1):29, 2023.
Liu XM#, Xia X#, Xifu Wang, Zhou J, Sung LA, Long JH, Geng XY, Zeng Z*, Yao WJ*. Tropomodulin1 expression increases upon maturation in dendritic cells and promotes their maturation and immune functions. Front Immunol. 11: 587441, 2021.
基金项目
目前主持1项国家自然科学基金面上项目,1项北京市自然科学基金面上项目。
