周源博士

预聘制助理教授、副研究员、博士生导师

北京大学基础医学院医学信息学系

E-mail:zhouyuanbioinfo@bjmu.edu.cn

 

研究方向

1. 疾病相关转录组数据的计算分析；

2. RNA修饰与表观转录组学的生物信息学研究。

 

个人简介

2010年本科毕业于首都师范大学生物科学专业，2015年于中国农业大学生物信息学专业获理学博士学位，后于北京大学医学部从事博士后研究。现就职于北京大学基础医学院医学信息学系，从事生物信息学研究，目前主要研究兴趣为转录组学（含非编码RNA）与表观转录组学数据的计算分析。先后开发了CCPPI、SRAMP等10余个生物信息学工具，总使用量超过4万人次。以（含共同）第一或通讯作者在Nucleic Acids Research, Briefings in Bioinformatics等专业期刊上发表SCI论文22篇，其它署名SCI论文15篇。

 

代表论文

1、Zhan Tong, Qinghua Cui, Juan Wang*, Yuan Zhou*. TransmiR v2.0: an updated transcription factor-microRNA regulation database. Nucl Acids Res，2018, in press, doi: 10.1093/nar/gky1023.

2、Jianwei Li*, Xiaofen Han, Yanping Wan, Shan Zhang, Yingshu Zhao, Rui Fan, Qinghua Cui, Yuan Zhou*. TAM 2.0: tool for microRNA set analysis. Nucl Acids Res, 2018, 2018,46(W1):W180-W185.

3、Chunmei Cui#, Weili Yang#, Jiangcheng Shi, Yong Zhou, Jichun Yang, Qinghua Cui*, Yuan Zhou*. Identification and analysis of human sex-biased microRNAs. Genomics, Proteomics Bioinformatics, 2018, 16(3): 200-211.

4、Yuan Zhou*, Qinghua Cui*. Comparative Analysis of Human Genes Frequently and Occasionally Regulated by m6A Modification. Genomics, Proteomics Bioinformatics, 2018, 16(2):127-135.

5、Wenjing Xu#, Yuan Zhou#, Guoheng Xu*, Bin Geng*, Qinghua Cui*. Transcriptome analysis reveals non-identical microRNA profiles between arterial and venous plasma. Oncotarget, 2017, 8(17):28471-28480.

6、Hong Li, Yuan Zhou*, Ziding Zhang*. Network Analysis Reveals a Common Host-Pathogen Interaction Pattern in Arabidopsis Immune Responses. Front Plant Sci, 2017, 8:893.

7、Shiping Yang, Hong Li, Fei He, Yuan Zhou*, Ziding Zhang*. Critical assessment and performance improvement of plant-pathogen protein-protein interaction prediction methods. Brief Bioinform, 2017, in press, doi: 10.1093/bib/bbx123.

8、Yuan Zhou*, Pan Zeng, Yan-Hui Li, Ziding Zhang, Qinghua Cui*. SRAMP: prediction of mammalian N6-methyladenosine (m6A) sites based on sequence-derived features. Nucl Acids Res, 2016,44(10):e91.

9、Yuan Zhou#, Ying-Si Zhou#, Fei He, Jiangning Song*, Ziding Zhang*. Can simple codon pair usage predict protein-protein interaction? Mol Biosyst, 2012, 8(5): 1396-1404.

10、Fei He#, Yuan Zhou#, Ziding Zhang*. Deciphering the Arabidopsis floral transition process by integrating a protein-protein interaction network and gene expression data. Plant Physiol, 2010, 153(4): 1492-1505.