学术信息
Functional characterization of ISL1 on insulin gene transcription regulation
发布日期：2007-06-26
生理与病生理学系及糖尿病中心学术活动
题目：Functional characterization of ISL1 on insulin gene transcription regulation
主讲人：周春燕教授
北京大学基础医学院副院长
生物化学与分子生物学系教授
时间：2007-6-29，Friday，11:30am
地点：生理楼三层会议室
周春燕教授，北京大学基础医学院副院长（主管科研），生物化学与分子生物学系教授。周教授于1986年获中国预防医学科学院病毒学研究所硕士学位后在我校生化学系任教，1994年获得英国剑桥大学病理系分子生物学博士学位，先后在英国剑桥大学外科系和英国剑桥Novartis Imutran分公司做Senior Scientist，主要从事干细胞分化分子机制及应用研究，现任中国生物化学与分子生物学会第三届医学专业委员会副理事长、北京市生物化学与分子生物学学会第五届常务理事。先后负责多项国家和省部级科研课题。代表性论文包括： Tao Li, Yanming Li, Zhuqing Jia, Ping Chen, Kangtao Ma, Chunyan Zhou*. Carboxyl-terminal of NKX2.5 impairs its interaction with p300. J. Mol. Biol. 2007, 370: 976-992. Zuoyan Wang, Ming Cui, Lijie Sun, Zhuqing Jia, Yun Bai, Kangtao Ma, Fengrong Chen*, Chunyan Zhou*. Angiopoietin-1 protects H9c2 cells from H2O2-induced apoptosis through AKT signaling. Biochemical and Biophysical Research Communications (BBRC). 2007, 359 (3): 685-690. Lijie Sun, Ming Cui, Zuoyan Wang, Xinheng Feng, Jieming Mao, Ping Chen, Kangtao Ma, Fengrong Chen*, Chunyan Zhou*. Mesenchymal stem cells modified with angiopoietin-1 improve remodelling in a rat model of acute myocardial infarction. Biochemical and Biophysical Research Communications (BBRC). 2007, 357 (3): 779-784. Siyang Peng, Weiping Wang, Jun Meng, Tao Li, Hui Zhang, Yanming Li, Ping Chen, Kangtao Ma, Chunyan Zhou*. ISL1 physically interacts with BETA2 to promote insulin gene transcriptional synergy in non-? cells. Biochim Biophys Acta. 2005, 1731: 154-159. Shun Lu, Weiping Wang, Xiaofei Wang, Zongmei Zheng, Ping Chen, Kangtao Ma, Chunyan Zhou*. Heterogeneity in predisposition of hepatic cells to be induced into pancreatic endocrine cells by PDX-1. World Journal of Gastroenterology. 2005, 11: 2277-2282.
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