北京大学基础医学院

院长论坛

报告题目：Integrating actin dynamics and Adhesion in cell migration and immune function

报告人：Clare Michal Waterman，Ph.D.

Director, Cell Biology and Physiology Center,

Chief, Laboratory of Cell and Tissue Morphodynamics,

National Heart, Lung, and Blood Institute

National Institutes of Health, Bethesda, MD.

时间：2018年 3 月12 日（星期一）上午10:30

地点：生化楼三层中厅

主持人：吴聪颖

报告人简介：

Dr. Clare M. Waterman is a cell biologist who has made seminal contributions to understanding the role of the cytoskeleton in cell migration. Her past work consists of novel findings related to the development of experimental approaches, the cytoskeletal elements of a cell, including microtubules and actin, and the extracellular matrix. She pioneered the invention and application of novel quantitative and super-resolution light microscopy methods, and utilized these tools to reveal the architectural blueprint and dynamics of protein-based nano-machines that self-assemble in cells to generate, organize, and transmit the forces that drive cell movement, and she defined molecular pathways governing the orchestration of these protein machines in space and time. This unique and innovative body of work constitutes a major advance in knowledge of the molecular and biophysical basis of cell movement. Dr. Waterman has received numerous awards and honours, including the Sackler International prize in Biophysics, the NIH Director’s Pioneer Award, and the Arthur S. Flemming Award for Public Service.