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AMPK,a Metabolic Tumor Suppressor?

生理与病理生理学系及糖尿病中心学术活动

题目:AMPK,a Metabolic Tumor Suppressor?

讲演人:Zhijun Luo, MD, Ph.D

                           Associate Professor

                          Department of Biochemistry

                          Boston University School of Medicine

时间:2008-9-26(Friday),12:00

地点:生理楼三层会议室

 

Education

8/83 M.D.,    Jiangxi Medical College, Nanchang, China.

8/86 M.Sc.    in Medical Genetics, Sun Yat-sen University of Medical Sciences, Guangzhou, China.

9/91 Ph.D.    in Biochemistry, Albert Einstein College of Medicine, New York.

Employment / Experience

10/91-10/92   Postdoctoral fellow, Department of Medicine, Albert Einstein College of Medicine, New York.

11/92-12/94   Postdoctoral fellow, Diabetes Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston.

1/95-8/97    Instructor, Diabetes Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston.

9/97-9/05   Assistant Professor, Diabetes & Metabolism Unit, Department of Medicine, and Department of Biochemistry, Boston University School of Medicine, Boston.

10/05-8/06   Associate Professor, Departments of Medicine and Biochemistry, Boston University School of Medicine, Boston.

9/06-6/08    Associate Professor, Departments of Genetics and Genomics, Medicine, and Biochemistry, Boston University School of Medicine, Boston.

7/08-present    Associate Professor, Departments of Biochemistry and Medicine, Boston, University School of Medicine, Boston.

Selected publication

1.        Xiang X, Zang M, Waelde CA, Wen R, and Luo Z. Phosphorylation of S338SYY341 regulates specific interaction between Raf-1 and MEK1. J. Biol. Chem 277: 44996-45003, 2002.

2.        Xu C. W. and Luo Z. Inactivation of Ras function by allele-specific peptide aptamers. Oncogene 21: 5753-5757, 2002.

3.        Luo Z, Saha AK, Xiang X, and Ruderman NB. AMPK, the metabolic syndrome and cancer. TIPS 26: 69-76, 2005.

4.        He M, Zhang J, Shao L, Huang Q, Chen J, Chen H, Chen X, Liu D, Luo Z. Upregulation of 14-3-3 isoforms in acute rat myocardial injuries induced by burn and  lipopolysaccharide. Clinical and Experimental Pharmacology and Physiology 33: 374–80, 2006.

5.        Guo W, Wong S, Xie W, Lei T, Luo Z. Palmitate Modulates Intracellular Signaling, Induces Endoplasmic Reticulum Stress, and Causes Apoptosis in Mouse 3T3-L1 and Rat Primary Preadipocytes. Am J Physiol Endocrinol Metab. 293:E576-86 2007.

 

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