北京大学基础医学院

院长论坛

报告题目：Targeting metabolic vulnerabilities for development of new antimicrobials

报 告 人：Choukri Ben Mamoun，Ph.D.

                            Professor of Medicine and Microbial Pathogenesis

                    Yale School of Medicine

                    Department of Internal Medicine

                    & Department of Microbial Pathogenesis

时          间：2019 年10 月19 日（星期六）上午10:00-11:00

地          点：生化楼三层中厅

主 持 人：鲁凤民教授

 

报告简介：

 

The Ben Mamoun Lab at Yale University focuses on understanding how pathogens import and utilize host nutrients for development, differentiation, and virulence. They focus on two important human diseases, malaria and babesiosis caused by protozoan parasites of the genus Plasmodium and Babesia, respectively. The lecture will be divided into two part: First, Prof. Ben Mamoun will describe studies that link metabolism of phospholipids to malaria development and pathogenesis. Specifically, he will present biochemical, genetic and structural data on an important lipid metabolic enzyme and efforts to target it for the development of new classes of antimicrobials. Second, Prof. Ben Mamoun will present a recent discovery in the lab of a novel mechanism by which Babesia parasites export proteins to the host, and strategies developed to discover new antiparasitic drugs.

 

 

 

欢迎师生参加！